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Vitamin K2 MK-4 from Ancestral Food:
Offers Benefits as Nature Intended – References

– References

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    1. Johanna GM et al. Associated with a Reduced Risk of CoronaryHeart Disease: The Rotterdam Study. The Journal of Nutrition, Volume 134, Issue 11, November 2004, Pages 3100–3105, Published: 01 November 2004 https://doi.org/10.1093/jn/134.11.3100
    2. Gancheva SM et al. Vitamin K2 Improves Anxiety and Depression but not Cognition in Rats with Metabolic Syndrome: a Role of Blood Glucose? Folia Med (Plovdiv). 2016 Dec 1;58(4):264-272. doi: 10.1515/folmed-2016-0032.
    3. HyungJetal. Vitamin K2 Supplementation Improves Insulin Sensitivity via Osteocalcin Metabolism: A Placebo-Controlled Trial. Diabetes Care 2011 Sep; 34(9): e147-e147. https://doi.org/10.2337/dc11-0551
    4. Ferland G. Vitamin K, an emerging nutrient in brain function. Biofactors. 2012 Mar-Apr;38(2):151-7. doi: 10.1002/biof.1004. https://doi.org/10.3945/an.111.001784
    5. Okamoto H. Vitamin K and rheumatoid arthritis. IUBMB Life. 2008 Jun;60(6):355-61. doi: 10.1002/iub.41.
    6. Sandberg M et al. NRF2-regulation in brain health and disease: implication of cerebral inflammation. Neuropharmacology. 2014 Apr; 0: 298–306. doi:10.1016/j.neuropharm.2013.11.004    
    7. Schlinsog W. Treatment of CTE using Emu Oil as source of Vitamin K2 MK-4 (Walkabout brand). Case Study, 2012.
    8. Asagi I et al. Menaquinone-4 enhances testosterone production in rats and testis-derived tumor cells. Lipids Health Dis. 2011; 10: 158. doi: 10.1186/1476-511X-10-158
    9. Peart K. Not Just Skin and Bones: Wrinkles Could Predict Women’s Bone Fracture Risk. YaleNews, 2011 June 6. https://news.yale.edu/2011/06/06/not-just-skin-and-bones- wrinkles-could-predict-women-s-bone-fracture-risk
    10. Vos M. Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency. Science. 2012 Jun 8; 336(6086):1306-10. doi:10.1126/science.1218632. https://core.ac.uk/download/pdf/34533525.pdf
    11. Bhalerao S et al. Vitamin K2 takes Charge.
      Science Vol 336. 2012 Jun 8;10.1126/science.1223812 https://www.ralf-kollinger.de/wp/wp- content/uploads/2014/02/Vitamin- K2-takes-charge.pdf
    12. Matrix Gla Protein
      European Molecular Biological Laboratory – European Bioinformatics Institute (EMBL-EBI), 2019 www.ebi.ac.uk
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    14. Vitamin K2-Dependent Proteins
      European Molecular Biological Laboratory – European Bioinformatics Institute (EMBL-EBI), 2019 www.ebi.ac.uk
    15. Suttie JW. Synthesis of vitamin K dependent proteins. FASEB J. 1993 Mar;7(5):445-52 PMIS 8462786
    16. Gijsbers BL et al. Effect of food composition on vitamin K absorption in human volunteers. Br J Nutr. 1996 Aug;76(2):223-9.
    17. Shanahan C. Deep Nutrition: Why your genes need traditional food. Big Box Books, 2009, p. 153, 233.
    18. Rheuame-Bleue K. Vitamin K2 and the Calcium Paradox: how a little known vitamin can save your life. 2012
    19. Davidson RT et al. Conversion of dietary phylloquinone to tissue menaquinone-4 in rats is not dependent on gut bacteria. J Nutr. 1998 Feb;128(2):220-3.
    20. Ronden J et al. Intestinal flora is not an intermediate in the phylloquinone- menaquinone-4 conversion in the rat. Biochimca et Biophysica Acta (BBA) – General Subjects. Volume 1379. issue 1, 8 January 1998, p. 69-75.
    21. Hirota, Y et al. Menadione (Vitamin K-3) Is a Catabolic Product of Oral Phylloquinone (Vitamin K-1) in the Intestine and a Circulating
      Precursor of Tissue Menaquinone-4 (Vitamin K-2) in Rats.       The Journal of Biological Chemistry. 2013, 288.10.1074/jbc.M113.477356.
    22. Human Health Effects of Menadione, Toxicology Data Network (TOXNET), 2019, https://toxnet.nlm.nih.gov/cgi- bin/sis/search/a?dbs+hsdb:@term+@DOCNO+3354
    23. Price, WA. Nutrition and Physical Degeneration.
      La Mesa, CA: Price-Pottenger Nutrition Foundation, 1939.
    24. VitaK Laboratories. Form 11.1: Result from Vitamin K measurements (Weston A. Price Foundation, June 2015) minKMeasurements120315-WestonPriceFoundation-foodsamples1
    25. Masterjohn C. On the Trail of the Elusive X-Factor: A Sixty-Two- Year-Old Mystery Finally Solved. The Weston A. Price Foundation, Published Online February 14, 2008
    26. Hiraike H et al. Distribution of K vitamins (phylloquinone and menaquinones) in human placenta and maternal and umbilical cord plasma. Am J Obstet Gyecol. 1988 Mar;158(3 Pt 1):5649. https://www.ncbi.nlm.nih.gov/pubmed/3348316
    27. VitaK Laboratories. Form 11.1: Result from Vitamin K measurements (Weston A. Price Foundation, April 2015) minKMeasurements120315-WestonPriceFoundation-foodsamples
    28. VitaK Laboratories. Form 11.1: Result from Vitamin K measurements (Weston A. Price Foundation, Oct-November 2015) minKMeasurements021015-WestonPriceFoundation-foodsamples
    29. Leichhardt L. Journal of an overland expedition in Australia – From Moreton Bay to Port Essington, a distance of upwards of 3000 miles, during the years 1844-1845. T. and W. Boone London, 1847. Epub 2002, University of Sydney Library. http://setis.library.usyd.edu.au/ozlit/pdf/p00050.pdf
    30. Vitamin K-Dependent Proteins: Biological Processes. European Molecular Biological Laboratory – European Bioinformatics Institute (EMBL-EBI), 2019 www.ebi.ac.uk
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    32. Ray AK et al. Loss of Gas6 and Axl signaling results in extensive axonal damage, motor deficits, prolonged neuro- inflammation, and less remeylination following cuprizone exposure. Glia. 2017 Dec:65(12):2051-2069.
      doi: 10.1002/glia.23214.
    33. Lasemi R et al. Vitamin K2 in multiple sclerosis patients. Wien Klin Wochenschr. 2018 May;130(9-10):307-313. doi: 10.1007/s00508-018-1328-x.
    34. Dulamea AO. Role of Oligodendrocyte Dysfunction in Demyelination, Remyelination and Neurodegeneration in Multiple Sclerosis. Adv Exp Med Biol. 2017; 958:91-127. doi: 10.1007/978-3-319-47861-6_7.

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